LOCUS       XP_001656178             215 aa            linear   INV 13-SEP-2007
DEFINITION  frataxin, putative [Aedes aegypti].
ACCESSION   XP_001656178
VERSION     XP_001656178.1  GI:157133106
DBSOURCE    REFSEQ: accession XM_001656128.1
KEYWORDS    .
SOURCE      Aedes aegypti (Stegomyia aegypti)
  ORGANISM  Aedes aegypti
            Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;
            Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea;
            Culicidae; Culicinae; Culicini; Aedes; Stegomyia.
REFERENCE   1  (residues 1 to 215)
  AUTHORS   Nene,V., Wortman,J.R., Lawson,D., Haas,B., Kodira,C., Tu,Z.J.,
            Loftus,B., Xi,Z., Megy,K., Grabherr,M., Ren,Q., Zdobnov,E.M.,
            Lobo,N.F., Campbell,K.S., Brown,S.E., Bonaldo,M.F., Zhu,J.,
            Sinkins,S.P., Hogenkamp,D.G., Amedo,P., Arsenburger,P.,
            Atkinson,P.W., Bidwell,S., Biedler,J., Birney,E., Bruggner,R.V.,
            Costas,J., Coy,M.R., Crabtree,J., Crawford,M., Debruyn,B.,
            Decaprio,D., Eiglmeier,K., Eisenstadt,E., El-Dorry,H.,
            Gelbart,W.M., Gomes,S.L., Hammond,M., Hannick,L.I., Hogan,J.R.,
            Holmes,M.H., Jaffe,D., Johnston,S.J., Kennedy,R.C., Koo,H.,
            Kravitz,S., Kriventseva,E.V., Kulp,D., Labutti,K., Lee,E., Li,S.,
            Lovin,D.D., Mao,C., Mauceli,E., Menck,C.F., Miller,J.R.,
            Montgomery,P., Mori,A., Nascimento,A.L., Naveira,H.F., Nusbaum,C.,
            O'Leary,S.B., Orvis,J., Pertea,M., Quesneville,H., Reidenbach,K.R.,
            Rogers,Y.H., Roth,C.W., Schneider,J.R., Schatz,M., Shumway,M.,
            Stanke,M., Stinson,E.O., Tubio,J.M., Vanzee,J.P.,
            Verjovski-Almeida,S., Werner,D., White,O., Wyder,S., Zeng,Q.,
            Zhao,Q., Zhao,Y., Hill,C.A., Raikhel,A.S., Soares,M.B.,
            Knudson,D.L., Lee,N.H., Galagan,J., Salzberg,S.L., Paulsen,I.T.,
            Dimopoulos,G., Collins,F.H., Bruce,B., Fraser-Liggett,C.M. and
            Severson,D.W.
  TITLE     Genome Sequence of Aedes aegypti, a Major Arbovirus Vector
  JOURNAL   Science 316 (5832), 1718-1723 (2007)
   PUBMED   17510324
REFERENCE   2  (residues 1 to 215)
  AUTHORS   Galagan,J., Devon,K., Henn,M.R., Severson,D.W., Collins,F.,
            Jaffe,D., Rounsley,S., DeCaprio,D., Kodira,C., Lander,E.,
            Crawford,M., Butler,J., Alvarez,P., Gnerre,S., Grabherr,M.,
            Kleber,M., Mauceli,E., Brockman,W., Young,S., LaButti,K.,
            Pushparaj,V., Koehrsen,M., Engels,R., Montgomery,P., Pearson,M.,
            Howarth,C., Zeng,Q., Yandava,C., Oleary,S., Alvarado,L., Nusbaum,C.
            and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2005) Broad Institute of MIT and Harvard, 320
            Charles Street, Cambridge, MA 02141, USA
REFERENCE   3  (residues 1 to 215)
  AUTHORS   Loftus,B.J., Nene,V.M., Hannick,L.I., Bidwell,S., Haas,B.,
            Amedeo,P., Orvis,J., Wortman,J.R., White,O.R., Salzberg,S.,
            Shumway,M., Koo,H., Zhao,Y., Holmes,M., Miller,J., Schatz,M.,
            Pop,M., Pai,G., Utterback,T., Rogers,Y.-H., Kravitz,S. and
            Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2005) The Institute for Genomic Research, 9712
            Medical Center Drive, Rockville, MD 20850, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EAT45831.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..215
                     /organism="Aedes aegypti"
                     /strain="Liverpool"
                     /db_xref="taxon:7159"
                     /chromosome="2"
     Protein         1..215
                     /product="frataxin, putative"
                     /calculated_mol_wt=24309
     Region          87..204
                     /region_name="Frataxin"
                     /note="Frataxin is a nuclear-encoded mitochondrial protein
                     implicated in Friedreich's ataxia (FRDA), an human
                     autosomal recessive neurodegenerative disease; Frataxin is
                     found in eukaryotes and in purple bacteria; lack of
                     frataxin causes iron to accumulate in the; cd00503"
                     /db_xref="CDD:29607"
     Site            order(89,97..98,101,105,108..109,115,121)
                     /site_type="other"
                     /note="putative iron binding site"
                     /db_xref="CDD:29607"
     CDS             1..215
                     /locus_tag="AaeL_AAEL002948"
                     /coded_by="XM_001656128.1:1..648"
                     /note="encoded by transcript AaeL_AAEL002948-RA"
                     /db_xref="VectorBase:AAEL002948-RA"
                     /db_xref="GeneID:5576595"
                     /db_xref="VectorBase:AAEL002948"
ORIGIN      
        1 mkrqkikaaq kqlfslyhat tmsllvsafq rgvrrlprcv svihqtcpes ahqplpggit
       61 verrvnpifr rhlssmnpnd fiavslidsi tfeavcsdtl eslcdyfeql veeaaflksa
      121 ditygdgvlt vnfgepygty vinrqspnrq iwlsspksgp krydfipdks kvnegfwlyk
      181 hdgvslhell qkeigvivqk evdflslphs krldn
//


